ABI serves as the coordinated infrastructure for the standardized collection, processing and banking, and allocation of high-quality biospecimens. ABI is responsible for providing full-service biospecimen banking operations including specimen collection and processing, complete specimen annotation (treatment and outcome information), storing and maintenance of up-to-date specimen inventory and specimen distribution.
Current activities and services include collecting and banking freshly-frozen tissue specimens from excess surgical material, providing fresh tissue specimens for viable cell studies, processing and banking of adult stem cells and other blood components, maintaining a tissue database with links to clinicopathological data, histological staining and pathological interpretation, and organizing patient consent and assuring regulatory compliance. As a centralized core service, ABI adds value through expertise, timeliness, standardization, accountability, protection of patient confidentially, and timely completion of research. All samples are stored according to industry best practices, in temperature-controlled, monitored, and alarmed environments in LN2 dewers or other freezers (e.g., -80C freezers) as appropriate to maximize resource integrity utilizing Current Good Tissue Practice (CGTP) whenever possible. The primary objective of the Biorepository is to provide a resource that contributes significantly to individual project goals. An advisory committee serves to guide policies, prioritize resources, and review service requests to ensure equitable usage.
The ABI inventory consists of human samples and related clinical data collected from research subjects participating in specific, IRB-approved clinical trials, archival pathological and diagnostic specimens collected under routine clinical care, and legacy specimens remaining in excess after IRB-approved clinical trial requirements have been met.
ABI has the following sample types: plasma, serum, DNA, RNA, red blood cells (RBC), and viable peripheral blood cells. The major specimen disease categories include: cardiovascular diseases, cancer, aging, pulmonary diseases, infectious diseases and autoimmune system disorders.
The Biorepository provides dedicated personnel, facilities, and experience to investigators with clinically annotated high-quality biospecimens. The structure of the Biorepository takes advantage of our extensive experience in managing large, multi-site biospecimen repositories to organize and manage the multi-site nature of the proposed Projects. The Biorepository has expertise in sample procurement, processing, banking, clinical annotation and informatics for all types of biological specimens and derivatives to support and manage the need for 'real' and 'virtual' tissue banking across Institutions and Projects. The Executive Director of the Biorepository, David Harris, PhD, is a nationally recognized basic scientist in the field of biobanking with more than 20 years of experience, including managing clinical repositories with numbers of samples in the hundreds of thousands. In addition to Dr. Harris, the Biospecimen portion of the Core will also be supported by Michael Badowski, PhD. He has five years’ experience in managing daily biorepository laboratory operations.
To access and query the complete specimen inventory click here.
David T Harris, PhD
1501 N Campbell Ave.
UAHS 6122, PO Box 245221
Michael Badowski, PhD
1501 N Campbell Ave
UAHS 6122, PO Box 245221